Health, Longevity & Biohacking
Horvath Reveals Omega-3 Supplements Rejuvenate Epigenetic Age in Rigorous Clinical Trial
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#112 How To Slow Biological Aging With a Multivitamin, Vegetables, & Omega-3 | Dr. Steve Horvath
"The most credible result was omega-3 on epigenetic clocks. A couple of epigenetic clocks picked it up. GrimAge version 2, PhenoAge, DunedinPACE also worked very well in that context."
Dr. Steve Horvath discussed a rigorous Swiss randomized controlled trial of 780 people aged 71+ that showed omega-3 supplementation (1 gram) significantly reversed epigenetic aging markers. This was the most robust finding among multiple interventions tested, including vitamin D and exercise. The effect was detected across multiple validated aging clocks including GrimAge2, PhenoAge, and DunedinPACE, lending strong credibility to the anti-aging benefits of omega-3.
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