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David Sinclair alleges endotoxin contamination derailed his lab’s NMN mouse studies

Modern Wisdom · “Age Reversal Is Coming.” Inside The First Human Trials - Dr David Sinclair · August 24, 2026
David Sinclair alleges endotoxin contamination derailed his lab’s NMN mouse studies
Modern Wisdom
Modern Wisdom
“Age Reversal Is Coming.” Inside The First Human Trials - Dr David Sinclair
""we found in my lab, which I don't think is in Andrea's paper, is that there is endotoxin in NMN bulk and supplements. Endotoxin comes from bacteria, causes inflammation.""
David Sinclair alleges some NMN and other NAD-precursor supplements can contain endotoxin, and says his lab discovered contamination during mouse longevity experiments. He says his team worked with manufacturers to improve purity and advises consumers to look for reputable suppliers, GMP standards and batch analytics.
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Modern Wisdom
Modern Wisdom

“Age Reversal Is Coming.” Inside The First Human Trials - Dr David Sinclair

August 24, 2026 · 2h 5m · 3 Egleze moments
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