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Hydrogen Water Produced Equivalent of 20% Caloric Restriction in Leptin-Deficient Mice Study

By Egleze Editorial Desk · Published May 11, 2026 · Updated May 11, 2026 · The Ultimate Human · 265. Tyler LeBaron: Hydrogen Water, Mitochondrial Health, Selective Antioxidants, & Longevity
Hydrogen Water Produced Equivalent of 20% Caloric Restriction in Leptin-Deficient Mice Study
The Ultimate Human
The Ultimate Human
265. Tyler LeBaron: Hydrogen Water, Mitochondrial Health, Selective Antioxidants, & Longevity

What was said

"Those given the hydrogen water, they were so much thinner than the other rodents were. I mean, those pictures in the article, you can just visibly tell the difference. In fact, the drinking of hydrogen-rich water in this case was equivalent to like a 20% caloric restriction. Mechanistically, they found that hydrogen increased FGF21, or fibroblast growth factor 21, which increases energy expenditure."

A study published in the Journal of Obesity showed hydrogen water produced fat loss equivalent to 20% caloric restriction in leptin-deficient mice fed high-fat diets, despite the animals continuing to overeat. The mechanism involved increasing fibroblast growth factor 21 to boost energy expenditure. LeBaron also noted that a 24-week human metabolic syndrome study showed modest weight loss specifically from fat mass along with improvements in triglycerides, cholesterol ratios, and inflammatory markers.

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Egleze verified who said this and where. The underlying claim has not been independently established by Egleze.

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The Ultimate Human
Episode
265. Tyler LeBaron: Hydrogen Water, Mitochondrial Health, Selective Antioxidants, & Longevity
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1:18:38
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The Ultimate Human
The Ultimate Human

265. Tyler LeBaron: Hydrogen Water, Mitochondrial Health, Selective Antioxidants, & Longevity

April 28, 2026 · 5 Egleze moments
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