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Lieberman warns GLP-1 weight-loss drugs can drive significant muscle loss

Modern Wisdom · Harvard Professor: “I Tried Every Diet. This Is By Far The Worst.” - Daniel Lieberman · August 15, 2026
Lieberman warns GLP-1 weight-loss drugs can drive significant muscle loss
Modern Wisdom
Modern Wisdom
Harvard Professor: “I Tried Every Diet. This Is By Far The Worst.” - Daniel Lieberman
"One of the big concerns about about GOP ones is that people not only lose fat, they also lose muscle and they and they seem to lose a lot of muscle. It's a bit like beriatric surgery too."
Lieberman says GLP-1 drugs are “game changers” for weight loss but warns they may also cause substantial lean-mass loss, raising later frailty risk, particularly as patients age. He says he and colleagues published on the issue in JAMA, and advises strength training for people using the medications to help preserve muscle.
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Modern Wisdom
Modern Wisdom

Harvard Professor: “I Tried Every Diet. This Is By Far The Worst.” - Daniel Lieberman

August 16, 2026 · 2h 8m · 6 Egleze moments
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