Health, Longevity & Biohacking
Huberman says alpha-GPC may aid late workouts but carry stroke risk
Huberman Lab
Your Top Health Questions Answered
What was said
"Increasing the amount of choline in your system can after a few biochemical steps increase the amount of TMAO that is circulating in your body. Now TMAO can be increased by any number of things, fish, meat, etc. Anything that increases choline levels can do this, but alpha GPC does it pretty potently."
Andrew Huberman says alpha-GPC (600–900mg) can be a non-caffeine option for late-day strength training, claiming it can boost focus without harming sleep and may slightly increase REM sleep. He cautions that raising choline may increase TMAO, and says one study linked long-term, high-dose use with higher stroke and cardiovascular risk; he adds that garlic may reduce TMAO production.
Verification status
Attributed speaker claim
Egleze verified who said this and where. The underlying claim has not been independently established by Egleze.
Source and context
Egleze verified who said this and where. The underlying claim has not been independently established by Egleze.
- Programme
- Huberman Lab
- Episode
- Your Top Health Questions Answered
- Clip time
- 6:03
- Original source
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Huberman Lab