Diary of a CEO
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The Scientist Who Scans Fathers' Brains: Parenthood Shrinks Your Brain, And Drops Testosterone 25%!

Diary of a CEO · 24 August 2026 · 1h 28m · 5 Egleze moments
The Scientist Who Scans Fathers' Brains: Parenthood Shrinks Your Brain, And Drops Testosterone 25%! ▶

What happened in this episode?

Steven Bartlett interviews developmental psychologist Dr Darby Saxbe about biological and behavioural changes around the transition to parenthood, with a focus on fathers. Saxbe describes research suggesting new fathers show grey matter volume reductions—“shrinking”—especially in brain networks linked to social cognition and reading infants’ cues, arguing the changes may reflect increased neural efficiency rather than impairment. She says her lab found greater brain changes among fathers who reported stronger bonding and more hands-on involvement.

Saxbe also discusses hormonal shifts, saying longitudinal studies indicate hands-on fathers typically experience about a 25% fall in testosterone, with some rebound as children age. She cautions against simplistic “testosterone equals masculinity” narratives and says her lab observed associations between higher post-birth testosterone and poorer relationship outcomes, while very low testosterone was linked with higher paternal postpartum depression symptoms.

On relationships, Saxbe outlines a lab methodology that included recording couple conflict during pregnancy. She says more negative conflict behaviours predicted more medically complex births based on later medical records and more stressful birth appraisals. She also describes findings on stress physiology, including associations between stronger couple cortisol linkage and lower marital satisfaction.

The conversation turns to declining fertility rates and to policy: Saxbe argues humans evolved as cooperative “alloparents” and says lack of universal paid parental leave in the US increases stress and constrains choices around childcare. Bartlett also discusses his own plans for fatherhood, including embryo freezing, and asks for practical advice on preparing for parenthood.

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Programme
Diary of a CEO
Published
24 August 2026
Duration
1h 28m
Original episode
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5 moments from this episode

Source-linked · editorially selected
01
Health, Longevity & Biohacking

Fatherhood ‘shrinks’ grey matter in social brain networks, study author says

at 2:48 · Attributed speaker claim
So we found that in fathers and this is similar to what's been observed in mothers, the brain is actually losing gray matter volume. So it is shrinking. So if I had stronger hands, I could probably squish this brain and make it look tinier.

Saxbe says her research found new fathers show grey matter volume reductions, particularly in the “mentalising network” involved in understanding others’ feelings and intentions, and in visual areas important for reading infant facial cues. She argues the volume reduction is not a deficit but reflects increased efficiency, and later adds her lab found more “profound” shrinkage among fathers reporting stronger prenatal bonding and more hands-on care after birth.

02
Health, Longevity & Biohacking

Hands-on fathers typically see about a 25% testosterone drop, researcher says

at 9:39 · Attributed speaker claim
typically men when their hands on as fathers show about a 25% drop in testosterone and some of the best studies of this have been done longitudinally in the Philippines. Before we had longitudinal studies people said well maybe lower testosterone men are just choosing to become fathers.

Saxbe says longitudinal studies, including work in the Philippines, show men’s testosterone typically drops by roughly a quarter when they become hands-on fathers, addressing earlier questions about whether lower-testosterone men simply self-select into parenthood. She also says her lab found higher post-birth testosterone in fathers was associated with partners reporting more relationship dissatisfaction and more intimate partner aggression, while very low testosterone was linked with higher paternal postpartum depression symptoms.

03
Health, Longevity & Biohacking

Study links negative couple conflict in pregnancy to more medically complex births

at 24:32 · Attributed speaker claim
And we found that when couples fought more negatively and less positively during pregnancy, >> during pregnancy >> during pregnancy, so you know, they're about 6 months into pregnancy. A few months later, when it's time to deliver the infant, they had more medically complex births. And they also appraised the births as more stressful.

Dr Darby Saxbe says her lab obtained hospital or birth-centre charts after delivery and found that couples who showed more negative and less positive conflict behaviours during pregnancy later had more medically complex births, alongside more stressful birth appraisals. She frames the finding as evidence that couple relationship functioning may be relevant to birth outcomes, not only maternal factors.

04
Science

Having two or three children linked to ‘younger’ brain age markers in later scans

at 38:13 · Attributed speaker claim
brain scans from people in their 50s and 60s and they find that both men and women who report having had more kids have markers of a younger looking brain age. So if you do a machine learning algorithm that adjusts for your chronological age and then you know takes what the scans looks like and uses that to estimate what they think your brain age is. You look relatively younger when you report having had more kids.

Saxbe points to brain-imaging studies of people in their 50s and 60s which, she says, find that parents reporting more children show markers consistent with a younger “brain age” when assessed using machine-learning estimates from scans. She adds that the apparent benefit is greatest around two or three children, with diminishing returns thereafter.

05
Society

US has no universal paid parental leave despite broad support, Saxbe says

at 1:25:24 · Attributed speaker claim
we do not have a universal paid leave policy for parents. That's at the federal level. There are some different policies at the state level. So every state has slightly different policies, but frequently what's most available to parents is unpaid disability leave that's provided by the state.

Asked about a systemic change to reduce loneliness and distrust, Saxbe argues for stronger parenting policy—especially paid parental leave—saying the US is an outlier without a universal federal paid leave entitlement. She says access is uneven by state and occupation, and that many mothers return to work within weeks because the main protections can be unpaid or limited.