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Six Weeks of Mild Sleep Loss Triggers Insulin Resistance and Hypertension

By Egleze Editorial Desk · Published June 8, 2026 · Huberman Lab · Eating for Better Sleep & Foods that Improve Metabolic Health | Dr. Marie-Pierre St-Onge
Six Weeks of Mild Sleep Loss Triggers Insulin Resistance and Hypertension
Huberman Lab
Huberman Lab
Eating for Better Sleep & Foods that Improve Metabolic Health | Dr. Marie-Pierre St-Onge

What was said

"We saw that insulin resistance was increased after 6 weeks of sleep restriction compared to adequate sleep. We saw insulin sensitivity was reduced. It was worse actually in postmenopausal women compared to premenopausal women. We saw blood pressure was increased. So those cardiometabolic outcomes were adversely impacted in free-living, mild, sustained sleep restriction for 6 weeks."

In a free-living study where good sleepers reduced nightly sleep by just 1.5 hours for six weeks, Dr. St-Onge documented increased insulin resistance and elevated blood pressure. Postmenopausal women showed worse metabolic outcomes than premenopausal women. The study demonstrates that chronic mild sleep restriction, common in modern life, produces measurable cardiometabolic disease risk even without extreme sleep deprivation.

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Egleze verified who said this and where. The underlying claim has not been independently established by Egleze.

Programme
Huberman Lab
Episode
Eating for Better Sleep & Foods that Improve Metabolic Health | Dr. Marie-Pierre St-Onge
Clip time
21:18
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From this episode
Huberman Lab
Huberman Lab

Eating for Better Sleep & Foods that Improve Metabolic Health | Dr. Marie-Pierre St-Onge

June 8, 2026 · 5 Egleze moments
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