Entertainment

Conan O'Brien Admits He's Failed to Take CBD Gummies Given to Him

Conan O'Brien Needs A Friend · Conan Vs. Edibles Part II · May 24, 2026

Conan O'Brien Needs A Friend

Conan Vs. Edibles Part II

"I have nibbled on the corner of the sleep one and nibbled on the corner. Literally, I want to say less than half. I think on 2 occasions nibbled on maybe a quarter of one. And it looks like a very tiny mouse got at one."

Conan O'Brien revealed that despite publicly committing to try cannabis gummies two weeks ago on his podcast, he has only consumed a tiny fraction of a single gummy. He admitted to turning the experience into a chore requiring scheduled calendar time, citing his strict Catholic upbringing and medical family background as reasons for his hesitation. The confession came after staff repeatedly pressed him for an update fans were awaiting.

About this episode

In this episode of Conan O'Brien Needs a Fan, host Conan O'Brien delivers a self-described "fan service" update on his much-anticipated attempt to try cannabis gummies, deviating from the show's usual fan interaction format. Two weeks after assistant Sona Movsesian gifted him multiple Camino brand gummies designed for sleep, relaxation, and energy, O'Brien confesses he has only nibbled on approximately one-quarter of a single sleep gummy on two separate occasions, feeling no effects. The comedian turns the admission into extended comedy, explaining how he has transformed the simple act of taking a gummy into an anxiety-inducing chore requiring calendar scheduling. O'Brien attributes his reluctance to his strict Catholic upbringing in a dry household and his father's cautious approach to medication, despite his father being a microbiologist specializing in antibiotic resistance. Sona and producer Eduardo push back, with Eduardo having previously called O'Brien "a little bitch" for his hesitation. The conversation spirals into riffs about O'Brien's comedic persona being dependent on his neuroses, his high tolerance for substances due to being a tall redhead, and hypothetical scenarios involving Amsterdam cafes, orgies, and his wife Liza's disapproval. O'Brien promises to eventually take a full gummy and report back, while worrying aloud that becoming relaxed might ruin the podcast's entire dynamic.

Key takeaways

O'Brien admitted he has only consumed about a quarter of one cannabis gummy over two weeks despite public commitment.
He cited his strict Catholic upbringing and his microbiologist father's cautious approach to medication as reasons for hesitation.
Staff member Eduardo previously called O'Brien a little bitch for his reluctance to try the gummies fans were awaiting.
O'Brien joked that becoming relaxed might destroy the podcast by eliminating the neurotic energy that fuels the comedy.
He claimed as a tall redhead he has high tolerance for substances including Ambien which he compared to throwing a Tic Tac into the sun.
O'Brien promised to eventually take a full Camino brand gummy and provide another update to fans.