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Health, Longevity & Biohacking

Fasting Expert Claims Birth Control Decimates Women's Microbiome and Hormones

Lewis Howes School of Greatness · How to Fast for Fat Loss, Hormones, and Better Sex | Dr. Mindy Pelz · May 15, 2026
Fasting Expert Claims Birth Control Decimates Women's Microbiome and Hormones
Lewis Howes School of Greatness
Lewis Howes School of Greatness
How to Fast for Fat Loss, Hormones, and Better Sex | Dr. Mindy Pelz
"It's horrible for the microbiome. It decimates the microbiome. And you need your microbiome to make serotonin. You need it for immune system. You need your microbiome to break down estrogen."
Dr. Mindy Pelz argued on the School of Greatness that birth control pills severely damage gut health and hormonal balance in women. She claimed that keeping women on birth control from adolescence to menopause prevents the brain-ovary hormonal pattern from ever establishing naturally, leading to serious long-term hormonal dysfunction. She cited the microbiome's essential role in producing serotonin and breaking down estrogen.

About this episode

On this episode of the School of Greatness, host Lewis Howes sat down with Dr. Mindy Pelz, a fasting expert and author of the bestseller Fast Like a Girl, which sold over 400,000 copies in its first year. The conversation centered on why traditional fasting protocols fail women and how aligning fasting with the menstrual cycle can restore hormonal balance, fertility, and metabolic health. Dr. Pelz revealed her own health crisis at age 45 when aggressive fasting caused her hormones to crash and her period to stop for months, sparking anxiety for the first time in her life. She reversed the damage within 90 days by cycling fasting intensity with her hormonal phases. The discussion covered the two energy systems humans rely on, the critical differences between male and female hormonal rhythms, and why women need different fasting, exercise, and recovery protocols than men. Dr. Pelz made controversial claims about birth control pills decimating the microbiome and preventing natural hormonal development. She explained the science behind menstrual synchrony through pheromones, the importance of oxytocin for cortisol regulation, and why progesterone requires women to nurture rather than push during the final week of their cycle. She also shared a dramatic patient case study of a 300-pound man who lost 175 pounds by changing when he ate rather than what he ate. Throughout, Dr. Pelz emphasized that women have been forced to live like men hormonally and that reclaiming cyclical living is the key to unlocking female health and power.

Key takeaways

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