Lewis Howes School of Greatness
Episode overview

How to Fast for Fat Loss, Hormones, and Better Sex | Dr. Mindy Pelz

Lewis Howes School of Greatness · 5 Egleze moments
How to Fast for Fat Loss, Hormones, and Better Sex | Dr. Mindy Pelz
Episode summary

On this episode of the School of Greatness, host Lewis Howes sat down with Dr. Mindy Pelz, a fasting expert and author of the bestseller Fast Like a Girl, which sold over 400,000 copies in its first year. The conversation centered on why traditional fasting protocols fail women and how aligning fasting with the menstrual cycle can restore hormonal balance, fertility, and metabolic health. Dr. Pelz revealed her own health crisis at age 45 when aggressive fasting caused her hormones to crash and her period to stop for months, sparking anxiety for the first time in her life. She reversed the damage within 90 days by cycling fasting intensity with her hormonal phases. The discussion covered the two energy systems humans rely on, the critical differences between male and female hormonal rhythms, and why women need different fasting, exercise, and recovery protocols than men. Dr. Pelz made controversial claims about birth control pills decimating the microbiome and preventing natural hormonal development. She explained the science behind menstrual synchrony through pheromones, the importance of oxytocin for cortisol regulation, and why progesterone requires women to nurture rather than push during the final week of their cycle. She also shared a dramatic patient case study of a 300-pound man who lost 175 pounds by changing when he ate rather than what he ate. Throughout, Dr. Pelz emphasized that women have been forced to live like men hormonally and that reclaiming cyclical living is the key to unlocking female health and power.

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5 moments from this episode

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01
Health, Longevity & Biohacking

Fasting Expert Claims Birth Control Decimates Women's Microbiome and Hormones

Dr. Mindy Pelz argued on the School of Greatness that birth control pills severely damage gut health and hormonal balance in women. She claimed that keeping women on birth control from adolescence to menopause prevents the brain-ovary hormonal pattern from ever establishing naturally, leading to serious long-term hormonal dysfunction. She cited the microbiome's essential role in producing serotonin and breaking down estrogen.

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02
Health, Longevity & Biohacking

Woman Nearly Entered Menopause at 45 Due to Extreme Fasting

Dr. Mindy Pelz revealed her own hormones crashed and her menstrual cycle stopped for 3-4 months at age 45 after a year of aggressive fasting including one meal a day and multiple 3-day water fasts annually. She only recovered after breaking down the menstrual cycle and adjusting fasting timing to match hormonal phases, regaining her cycle within 90 days. This personal health crisis led her to develop the fasting protocols in her book Fast Like a Girl.

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03
Health, Longevity & Biohacking

Women's Bodies Stop Reproduction When They Don't Feel Safe Emotionally

Dr. Pelz explained that women struggling to conceive may be experiencing their body's protective response to stress and unsafe environments, including unresolved trauma and toxic thought patterns. She shared a story of a reproductive specialist who told a patient struggling for a year to simply stop doing so much and reduce stress, resulting in pregnancy within a month. Pelz argued that subconscious awareness of being in the wrong relationship could also prevent conception.

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04
Health, Longevity & Biohacking

Patient Lost 175 Pounds Eating Buffalo Wings by Changing When He Ate

Dr. Pelz shared the transformation story of a 300-pound man who initially drank 12 sodas daily and ate primarily fast food. By compressing his eating into progressively smaller windows through intermittent fasting without initially restricting food choices, he lost 13 pounds the first month while still consuming the same foods. Over time, as his microbiome changed, his food preferences naturally shifted and he ultimately lost 175 pounds.

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05
Health, Longevity & Biohacking

Women Sync Menstrual Cycles Through Pheromones When Living Together

Dr. Pelz explained the scientific phenomenon of menstrual synchrony among women in families or close communities, attributing it to pheromone detection that triggers hormonal alignment. She emphasized this as evidence of how adaptable and environment-responsive the female hormonal system is, constantly adjusting to external factors including the presence of other women.

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