Health, Longevity & Biohacking
Dr Jared Rutter says MPC was identified after decades of uncertainty
Huberman Lab
How Mitochondria Control Your Metabolism | Dr. Jared Rutter
"It's been known for, 60 or 70 years that mitochondria must have a carrier to enable pyruvate to get in, but it was not identified what that protein was, how it worked."
Dr Jared Rutter says the mitochondrial pyruvate carrier (MPC) transports pyruvate across the mitochondrial membrane for oxidation. He recalls that biochemists inferred such a carrier for 60–70 years, but the responsible proteins were only identified more recently through lab work including his group’s.
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Huberman Lab