← All stories
Health, Longevity & Biohacking

Dr Jared Rutter says MPC was identified after decades of uncertainty

By Egleze Editorial Desk · Published September 7, 2026 · Huberman Lab · How Mitochondria Control Your Metabolism | Dr. Jared Rutter
Dr Jared Rutter says MPC was identified after decades of uncertainty
Huberman Lab
Huberman Lab
How Mitochondria Control Your Metabolism | Dr. Jared Rutter

What was said

"It's been known for, 60 or 70 years that mitochondria must have a carrier to enable pyruvate to get in, but it was not identified what that protein was, how it worked."

Dr Jared Rutter says the mitochondrial pyruvate carrier (MPC) transports pyruvate across the mitochondrial membrane for oxidation. He recalls that biochemists inferred such a carrier for 60–70 years, but the responsible proteins were only identified more recently through lab work including his group’s.

Verification status

Attributed speaker claim

Egleze verified who said this and where. The underlying claim has not been independently established by Egleze.

Source and context

Egleze verified who said this and where. The underlying claim has not been independently established by Egleze.

Speaker
Dr. Jared Rutter · guest
Programme
Huberman Lab
Episode
How Mitochondria Control Your Metabolism | Dr. Jared Rutter
Clip time
53:39
Original source
Watch the source segment →
From this episode
Huberman Lab
Huberman Lab

How Mitochondria Control Your Metabolism | Dr. Jared Rutter

September 7, 2026 · 2h 3m · 1 Egleze moments
Read episode summary and key points →
More stories More from Huberman Lab