Health, Longevity & Biohacking
Visceral fat may predict fatty liver risk independent of BMI, Attia says
Peter Attia Drive
Metabolic liver health: how to assess risk, catch dysfunction early, and more (AMA 88 sneak peek)
"So in one cohort visceral fat area which could be estimated by CT scans um predicted steattosis independent of BMI and liver enzymes. So patients with greater than 200 cm squared of visceral fat had a 7 and a halffold greater increase of liver steattosis when compared to people below 100 cm squared."
Peter Attia argues that visceral adiposity is a major modifier of metabolic liver disease risk because it drains into the portal vein, delivering metabolites more directly to the liver. He cites cohort data in which CT-estimated visceral fat area was associated with steatosis risk independent of BMI and liver enzymes, including a reported 7.5-fold difference comparing >200 cm² versus <100 cm².
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Peter Attia Drive