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Otvos says unpublished Diabetes Prevention Program analysis found LPIR outperformed insulin

By Egleze Editorial Desk · Published August 3, 2026 · Peter Attia Drive · 402 ‒ NMR blood analysis: how mortality risk and more can be assessed from a single blood sample
Otvos says unpublished Diabetes Prevention Program analysis found LPIR outperformed insulin
Peter Attia Drive
Peter Attia Drive
402 ‒ NMR blood analysis: how mortality risk and more can be assessed from a single blood sample

What was said

""the study that shows it the best is one that unfortunately hasn't been published yet. It's it got very close to having the manuscript be written. It's in the diabetes prevention program.""

Otvos says analyses using stored samples from the Diabetes Prevention Program (DPP) found the NMR-derived LPIR score predicted diabetes risk better than fasting insulin, and showed lifestyle intervention reduced LPIR more than metformin. He adds later that the work has not been published, attributing delays in part to the primary author’s recent death.

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Egleze verified who said this and where. The underlying claim has not been independently established by Egleze.

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Peter Attia Drive
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402 ‒ NMR blood analysis: how mortality risk and more can be assessed from a single blood sample
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Peter Attia Drive
Peter Attia Drive

402 ‒ NMR blood analysis: how mortality risk and more can be assessed from a single blood sample

August 3, 2026 · 2h 27m · 7 Egleze moments
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