Health, Longevity & Biohacking
Huberman says brief sermorelin use spiked his PSA and suppressed REM sleep
Tim Ferriss Show
All Things Peptides — Dr. Andrew Huberman
"I've tried Smurellin very briefly. Dramatically increased my slowwave deep sleep. Nuked my REM sleep. This is a common theme. Spiked my prostate specific antigen. I've never had any problems with PSA. I came off it. PSA went back to normal."
Huberman recounts trying the growth-hormone secretagogue sermorelin and experiencing what he describes as a large increase in slow-wave sleep alongside a collapse in REM sleep. He also says his prostate-specific antigen (PSA) rose during use and returned to normal after stopping, adding he has not received a mechanistic explanation and would not repeat the experiment.
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Tim Ferriss Show