Lewis Howes School of Greatness
Episode overview

ADHD Doctor: How To Hack Your Brain For Better Focus | Dr. Sasha Hamdani

Lewis Howes School of Greatness · 1h 18m · 4 Egleze moments
ADHD Doctor: How To Hack Your Brain For Better Focus | Dr. Sasha Hamdani
Episode summary

Psychiatrist and ADHD specialist Dr Sasha Hamdani joins Lewis Howes to discuss how ADHD is diagnosed, why symptoms are often confused with stress, trauma responses, anxiety, depression, hormonal changes and medical conditions, and why she believes ADHD is better understood as a broader regulation issue rather than simply an “attention deficit”. Hamdani describes current diagnostic practice as heavily reliant on clinical history and longitudinal patterns, and argues that criteria originally built around observable hyperactivity in young boys can miss internal symptoms such as emotional dysregulation, particularly in women.

She alleges that some patients cycle through multiple antidepressants before ADHD is considered, criticising clinicians who refuse to evaluate ADHD until anxiety or depression is controlled. Hamdani also claims the average age of diagnosis differs sharply by sex, saying boys are often diagnosed in early childhood while women may not be diagnosed until their mid-30s, sometimes after recognising symptoms in their children.

The conversation also focuses on rejection sensitive dysphoria (RSD) and emotional sensitivity, with Hamdani outlining a simple brain-based model involving an overactive amygdala and an under-responsive prefrontal cortex during perceived threat. She shares personal experiences: being given ADHD medication as a child without fully understanding what it was, and later learning to connect emotional overwhelm with functional impairment. Practical suggestions include matching coping tools to how dysregulation presents (for her, movement can help interrupt spirals), and approaching a partner’s distress with calm curiosity rather than commands to “calm down”.

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4 moments from this episode

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02
Health, Longevity & Biohacking

Psychiatrist describes patients on ‘10th antidepressant’ before ADHD is considered

Dr Sasha Hamdani says she has seen patients prescribed multiple antidepressants before clinicians consider an ADHD assessment, which she frames as a cycle of misdiagnosis. She criticises the practice of deferring ADHD evaluation until anxiety or depression is treated, arguing it can delay appropriate care when ADHD-related emotional dysregulation is the underlying issue.

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03
Health, Longevity & Biohacking

Hamdani claims women are typically diagnosed with ADHD far later than men

Dr Sasha Hamdani claims the average age of ADHD diagnosis is around 6–8 for males versus about 35 for females, arguing women are often misdiagnosed with anxiety or depression or dismissed as “hormonal”. She attributes the gap to diagnostic criteria based on hyperactive boys, hormonal effects on dopamine, and social pressures that lead girls and women to mask symptoms.

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04
Health, Longevity & Biohacking

ADHD specialist says her parents gave her medication as a ‘vitamin’

Dr Sasha Hamdani says she was diagnosed with ADHD in fourth grade but did not understand she was taking ADHD medication, which she recalls her parents presented as a “vitamin”. She says she later felt “extremely betrayed” when she learned what it was during medical school, describing the episode as something her parents “could have handled… better”.

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