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Transplanting Human Poo from Depressed Patients Can Induce Depression-Like Behavior in Mice

By Egleze Editorial Desk · Published July 2, 2026 · ZOE Science & Nutrition · How to build a better brain: Your doctor won't mention THIS for mood, memory and dementia
Transplanting Human Poo from Depressed Patients Can Induce Depression-Like Behavior in Mice
ZOE Science & Nutrition
ZOE Science & Nutrition
How to build a better brain: Your doctor won't mention THIS for mood, memory and dementia

What was said

"If you take poo from people with major depressive disorder or with schizophrenia and you put them into mice compared to poo from healthy people, you can induce what's called the behavioral phenotype. Basically, you can make a mouse behave as if it has depression or schizophrenia, you can see some of the biochemical changes."

Professor Felice Jacka reveals that fecal transplants from humans with mental disorders can cause mice to display similar behavioral symptoms. This demonstrates that gut microbes may causally drive mental illness, not just correlate with it, fundamentally challenging the notion that depression is purely psychological.

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Egleze verified who said this and where. The underlying claim has not been independently established by Egleze.

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Egleze verified who said this and where. The underlying claim has not been independently established by Egleze.

Programme
ZOE Science & Nutrition
Episode
How to build a better brain: Your doctor won't mention THIS for mood, memory and dementia
Clip time
15:50
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ZOE Science & Nutrition
ZOE Science & Nutrition

How to build a better brain: Your doctor won't mention THIS for mood, memory and dementia

July 2, 2026 · 1h 1m · 5 Egleze moments
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