← All stories
Health, Longevity & Biohacking

Psychiatrist Claims No Evidence Depression is Caused by Chemical Imbalance

Triggernometry · The Truth About Depression - Dr Joanna Moncrieff · June 24, 2026
Psychiatrist Claims No Evidence Depression is Caused by Chemical Imbalance
Triggernometry
Triggernometry
The Truth About Depression - Dr Joanna Moncrieff
"There is no evidence that you have a chemical imbalance in your brain if you are depressed. So therefore, there's no evidence that that antidepressant you're being offered is going to correct that. They haven't asked that question about what antidepressants might be doing by just messing about with our normal brain chemistry."
Dr. Joanna Moncrieff, a psychiatrist who published a major 2022 review, stated definitively that depression has not been proven to be caused by a chemical imbalance despite decades of this being the dominant narrative. She argued the psychiatric profession avoided investigating what long-term antidepressant use does to normal brain chemistry because they were focused on the false premise of correcting an imbalance. This challenges the foundational justification for prescribing antidepressants to millions.
From this episode
Triggernometry
Triggernometry

The Truth About Depression - Dr Joanna Moncrieff

August 3, 2026 · 5 Egleze moments
Read episode summary and key points →

More moments from this episode

Health, Longevity & BiohackingPsychiatric Profession Actively Shut Down Chemical Imbalance Debate Despite Knowing TruthHealth, Longevity & BiohackingPharmaceutical Industry Deliberately Spread Chemical Imbalance Theory to Sell SSRIsHealth, Longevity & BiohackingOne in Five Adults in England Taking Antidepressants Despite Lack of EvidenceHealth, Longevity & BiohackingPharmaceutical Companies Now Pushing Opioids and Ketamine as Antidepressants for Profit
More stories More from Triggernometry