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Exercise Shows Equal Effectiveness to Antidepressants in Clinical Trials for Depression

By Egleze Editorial Desk · Published June 14, 2026 · ZOE Science & Nutrition · What inflammation is really doing to your mind, body and 5 ways to protect your brain | Prof Ed Bullmore
Exercise Shows Equal Effectiveness to Antidepressants in Clinical Trials for Depression
ZOE Science & Nutrition
ZOE Science & Nutrition
What inflammation is really doing to your mind, body and 5 ways to protect your brain | Prof Ed Bullmore

What was said

"People have done randomized trials of physical training, physical fitness, and have demonstrated moderately effective shifts in mood equivalent to what you'd see with antidepressant drugs."

Professor Bullmore cites randomized controlled trials showing physical exercise produces mood improvements equivalent to pharmaceutical antidepressants for treating depression. He explains the mechanism works through exercise's anti-inflammatory effects on the body, which then impacts brain function. This suggests doctors could prescribe exercise as an equally effective alternative to medication for many patients.

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Egleze verified who said this and where. The underlying claim has not been independently established by Egleze.

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Egleze verified who said this and where. The underlying claim has not been independently established by Egleze.

Programme
ZOE Science & Nutrition
Episode
What inflammation is really doing to your mind, body and 5 ways to protect your brain | Prof Ed Bullmore
Clip time
45:38
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ZOE Science & Nutrition
ZOE Science & Nutrition

What inflammation is really doing to your mind, body and 5 ways to protect your brain | Prof Ed Bullmore

June 11, 2026 · 5 Egleze moments
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