← All stories
Health, Longevity & Biohacking

American Heart Association Adds Depression as Fourth Major Risk Factor for Heart Disease

Huberman Lab · Essentials: Psychedelics & Neurostimulation for Brain Rewiring | Dr. Nolan Williams · June 4, 2026
American Heart Association Adds Depression as Fourth Major Risk Factor for Heart Disease
Huberman Lab
Huberman Lab
Essentials: Psychedelics & Neurostimulation for Brain Rewiring | Dr. Nolan Williams
"Recently, the American Heart Association added depression as the fourth major risk factor for coronary artery disease, right? So alongside the risk factors that we know: hypertension, high blood pressure, hyperlipidemia, high cholesterol, and diabetes, you know, high blood sugar. Those three have been on the list for a long time, and depression ended up, you know, being added to the list as the fourth one."
Dr. Williams reported that depression now joins hypertension, high cholesterol, and diabetes as a recognized major cardiovascular risk factor. His lab's research demonstrates direct brain-heart connections, showing that transcranial magnetic stimulation over mood regulatory regions can decelerate heart rate, revealing measurable physiological links between depression and cardiac outcomes.
From this episode
Huberman Lab
Huberman Lab

Essentials: Psychedelics & Neurostimulation for Brain Rewiring | Dr. Nolan Williams

August 3, 2026 · 5 Egleze moments
Read episode summary and key points →

More moments from this episode

Crime & JusticeBrazilian Prison Study Shows Ayahuasca Reduced Recidivism Rates Compared to Control GroupHealth, Longevity & BiohackingPsychiatrist Declares Chemical Imbalance Theory of Depression Wrong, Proposes Circuit-Based ModelHealth, Longevity & BiohackingStanford Psychiatrist Reports TMS Depression Treatment Achieves 60-90% Remission in Five DaysHealth, Longevity & BiohackingFirst Human Study Shows Ibogaine Induces Forgiveness of Moral Injury in Special Forces Veterans
More stories More from Huberman Lab