What happened in this episode?
In this short excerpt, guest Ben Lamm discusses what he describes as rapid scaling in his organisation’s gene-editing delivery capacity. He says that what used to be considered a notable milestone — “20 edits delivered” — is still something most of “bioarma and academia” would celebrate, but claims his team is now “consistently” delivering “300 plus” edits at “90 plus% efficiency”. Lamm adds that the 300+ figure was true “a year ago” and that they are currently “testing thousand” edited deliveries, characterising the progress as an “exponential growing curve” while repeatedly warning that it may not continue and that current tests may not succeed.
The conversation also touches on the technical and economic crossover point where “large cargo swaps” combined with DNA synthesis may become a better approach than other editing strategies. Lamm argues that some organisations working in that space lack a “business driver” to synthesise DNA beyond a certain scale, and says his team has started doing DNA synthesis internally. Diamandis summarises the implied trajectory as “trippling year-over-year base edits,” and Lamm says he thinks it is “highly likely” they will reach the 1,000-edit level, though he notes early indicators have “low efficiency” but that “it’s working.”