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Dr. Daniel Amen | Club Random with Bill Maher

Club Random · 21 September 2026 · 1h 43m · 3 Egleze moments
Dr. Daniel Amen | Club Random with Bill Maher ▶

What happened in this episode?

Bill Maher interviews psychiatrist and brain-imaging promoter Dr Daniel Amen about what Amen calls a coming shift towards “brain-based” psychiatry. Amen argues that psychiatrists are unusual among medical specialists in that they “never look at the organ they treat”, and says his use of SPECT imaging changed his clinical practice; he claims his organisation now holds a database of 300,000 scans from 155 countries and that the American Psychiatric Association has produced a position paper calling for biomarkers including imaging.

A large portion of the discussion centres on substances and brain health. Maher, who says cannabis has been beneficial for him, presses Amen on marijuana’s harms; Amen says he has published findings on 1,000 users showing reduced brain activity and cites a separate study of 1,000 users, and warns that teenage use is associated with later anxiety, depression, suicide and psychosis. They also touch on sleep, with Amen saying alcohol and marijuana reduce REM sleep.

Amen discusses head trauma in sport, saying he has scanned and treated 400 NFL players and that 80% improved on a rehabilitation plan, disputing the view that CTE is inevitably progressive and untreatable. In a controversial exchange on vaccines and autism, Maher argues for a ‘reasonable middle’ position on side effects; Amen claims he has seen brain scans he describes as vaccine-related injury while stressing it is uncommon. The pair also discuss youth mental health, loneliness, pornography exposure via devices, and proposals to limit children’s access to social media.

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Named speakers identified in Egleze's source-linked moments from this episode.

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Programme
Club Random
Published
21 September 2026
Duration
1h 43m
Original episode
Open the original source ↗

Egleze verifies the speaker, source and timestamp for each linked moment. Unless a moment is explicitly marked independently verified, statements remain attributed claims by the named speaker rather than established facts.

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3 moments from this episode

Source-linked · editorially selected
01
Health, Longevity & Biohacking

Dr Daniel Amen cites his studies suggesting lower brain activity in heavy cannabis users

Dr Daniel Amen · at 20:18 · Attributed speaker claim
I published a study on a thousand marijuana users every area of their brain is i know them all in activity and i get so much engagement when i post about marijuana and people go oh you just need to get high an independent group on another thousand marijuana users that learning and memory centers lower in activity.

Dr Daniel Amen tells Bill Maher he published a study of 1,000 marijuana users which he says showed reduced activity across brain areas, and he cites an “independent group” analysis of another 1,000 users that he says found lower activity in learning and memory centres.

02
Health, Longevity & Biohacking

Dr Daniel Amen links teen cannabis use to higher mental-health risks

Dr Daniel Amen · at 21:14 · Attributed speaker claim
If you smoke as a teenager, you use marijuana as a teenager in your 20s, increased risk of anxiety, depression, suicide, and psychosis.

Dr Daniel Amen says using cannabis during the teenage years and into the 20s is associated with increased risks including anxiety, depression, suicidality and psychosis. He also says the brain is not fully developed until around the mid-20s.

03
Health, Longevity & Biohacking

Dr Daniel Amen says he has seen rare vaccine-related brain scans

Dr Daniel Amen · at 1:22:31 · Attributed speaker claim
Well, and I have vaccine damaged brains that I have scanned of kids who parents say are normal. They got the vaccine and their brain looks terrible, but it's not the norm. For sure, it's not the norm.

Dr Daniel Amen says he has scanned children whose parents reported changes after vaccination, and claims their brain scans looked severely affected. He adds that such cases are uncommon and that vaccines are generally safe despite possible side effects.